![]() ![]() Among 6944 patients, PMI occurred in 1058 patients (15.2%). The findings were validated in two independent cohorts. Using logistic regression, three models were derived: Model 1 including patient- and procedure-related information, Model 2 adding routinely available laboratory values, and Model 3 further adding preoperative hs-cTnT concentration. Perioperative myocardial infarction/injury was centrally adjudicated by two independent cardiologists using serial measurements of hs-cTnT. All other authors declare that they have no conflict of interest with this study.Īmong prospectively recruited patients at high cardiovascular risk (age ≥65 years or ≥45 years with preexisting cardiovascular disease), PMI was defined as an absolute increase in high-sensitivity cTnT (hs-cTnT) concentration of ≥14 ng/L (the 99th percentile) above the preoperative concentration. reports grants from the Swiss National Science Foundation, the Swiss Heart Foundation, the University of Basel, and the University Hospital Basel for this study, as well as grants, personal fees, and nonfinancial support from several diagnostic companies, outside the submitted work. reports grants from the Swedish Research Council, ALF-grants, Linköping University. reports research support as well as speaker honoraria from Siemens Healthineers, Abbott Diagnostics, and Beckman Coulter. reports grants from Forschungsfond Kantonsspital Aarau, during the conduct of the study. reports grants from the University of Basel and nonfinancial support from Roche Diagnostics, during the conduct of the study. ![]() reports grants from the Swiss Heart Foundation, grants from the Fundacao de Apoio a Pesquisa do estado de Sao Paulo, Brasil (FAPESP), and personal fees from Roche, outside the submitted work. reports research grants from Roche Diagnostics, the Swiss Heart Foundation, and the University Hospital Basel during the conduct of this study.
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